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Assessment of Dementia

Is this Dementia? | Is this just OLD AGE? | Stages of Dementia
Probable Causes | Differential Diagnosis | Risk Factors

 

Family Means Everything

Is this Dementia?
The purpose of making as accurate a diagnosis as possible of the cause of dementia is twofold, first to provide information to the client/family/caregivers, and second, to rule out any potentially treatable or reversible factors.

Confirm whether dementia is present

  • Assessment of impaired mental status (video clip 1, video clip 2) and function in older adults is defined by loss with functional decline.
    • normal mental status with normal function - no dementia
    • impaired mental status with normal function - may have some type of mental illness
    • normal mental status with impaired function - rule out physical causes
    • impaired mental status with impaired function - probable dementia; proceed with dementia evaluation
(Adapted from AHCPR: Early Identification of Alzheimer's Disease and Related Dementias: coa.kumc.edu)

More Information: http://www.americangeriatrics.org/products/positionpapers/aan_dementiaPF.shtml

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Is this Just "Old Age"?

Early signs of dementia
  • memory and concentration
    • normal : periodic minor memory lapses or forgetfulness, occasional lapses in attention or concentration
    • dementia : misplacement of important items, confusion with performance of simple tasks, difficulty making routine decisions, confusion about month or season
  • mood and behavior
    • normal : temporary sadness or anxiety based on appropriate or specific cause, changing interests, increasingly cautious behavior
    • dementia : unpredictable mood changes, increasing loss of outside interests, depression/anger/confusion in response to change, denial of symptoms
Later signs of dementia
  • language and speech
    • normal : unimpaired language skills
    • dementia : difficulty completing sentences or finding the right words, inability to understand the meaning of words, reduced and/or irrelevant conversation
  • movement and coordination
    • normal : increasing caution in movement, slower reaction times
    • dementia : visibly impaired movement or coordination, including slowing of movements, halting gait, and reduced sense of balance
  • other symptoms
    • normal : normal sense of smell, no abnormal weight changes in men or women
    • dementia : impaired sense of smell, severe weight loss (particularly in females)

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Stages of Dementia are classified according to the level of functional impairment and the subsequent ability to perform specific functions .

  1. Questionable - borderline functioning in several areas but definite impairment in none
  2. Mild - likely to have difficulties with balancing a checkbook, preparing a complex meal, or managing a difficult medication schedule
  3. Moderate - difficulties with simpler food preparation, household cleanup, and yard work; may require assistance with some aspects of self-care (e.g., reminders to use the bathroom, help with fasteners or shaving)
  4. Severe - considerable assistance with personal care, including feeding, grooming, and toileting
  5. Profound - largely oblivious to their surroundings and almost totally dependent on caregivers
  6. Terminal - generally bed bound, require constant care, and are susceptible to accidents and infectious diseases, which often prove fatal

Disease Process
The development of multiple cognitive deficits manifested by both:

  • Memory impairment - impaired ability to learn new information or to recall previously learned information
  • One (or more) of the following cognitive disturbances:
    • Amnesia - loss of memory; repeats questions often; misplaces objects; may be described by caregiver as frustrating or paranoid.
    • Aphasia - language disturbances; inability to speak or understand; cannot follow directions; won't engage in conversation; described by caregiver as uncooperative or withdrawn
    • Apraxia - impaired ability to carry out motor activities despite intact motor function; loss of ability to coordinate learned movements; cannot use utensils or toilet, cannot dress; may be described by caregiver as incontinent, uncooperative, won't eat
    • Agnosia - failure to recognize or identify objects despite intact sensory function; inability to recognize what is seen; cannot recognize faces, home. or familiar objects; may be described by caregiver as frightened, combative, wandering, paranoid
    • Disturbance in executive functioning (i.e., planning, organizing, sequencing, abstracting)
(Source: Alzheimer's Association. Key Elements of Dementia Care. Chicago, IL: Alzheimer's Disease and Related Disorders Association, Inc. 1997; coa.kumc.edu)

Manifestation of disease
The cognitive deficits noted each cause significant impairment in social or occupational functioning and represent a significant decline from a previous level of functioning
  • Gradual withdrawal from activities (due to forgetfulness regarding activity performance)
  • Increased tendency to misplace things
  • Narrowed interests and loss of initiative
  • Decreased tolerance of new ideas or changes in routine (often due to increased confusion and decreased ability to perform)
  • Self-centered thoughts
  • Increased restlessness or apathy
  • Deterioration of language and abstract thought processing
  • Inconsistent performance of tasks of daily living

(Source: Medscape Nursing, 2001)

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Probable Causes of Dementia
  • Alzheimer's Disease
  • Progressive supranuclear palsy
  • Lewy Body Disease
  • Multi-infarct (vascular) dementia
  • Drug, alcohol, or anoxic encephalopathy/dementia
  • Pick's Disease
  • Huntington's Disease
  • Senile dementia
  • Parkinson's Disease
  • Pseudodementia
  • Organic brain syndrome
  • Senile memory loss

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Differential Diagnosis: Conditions that can be reversed or improved
  • Depression
  • Delirium
    • medications
    • medical illness
      • hypothyroidism
      • B12 deficiency
      • syphilis
      • metabolic disorders
  • Comorbid Diseases
    • Hypertension
    • Stroke
    • Parkinson's Disease
  • Treatable dementia causes
    • Normal pressure hydrocephalus
    • Intoxication
    • CNS infections
    • Nutritional disorders
    • Vascular diseases
    • Space-occupying lesions

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Risk Factors
  • Higher Prevalence
    • advanced age
    • family history
    • lower educational level
    • high cholesterol
    • female gender (studies inconsistent)
    • hypertention (studies inconsistent)
  • Lower Prevalence due to potential protective relationship
    • hormone replacement therapy
    • anti-inflammatory use
    • moderate alcohol consumption
  • Other
    • environmental factors - infections, metals, industrial, or other toxins
    • infectious organisms - slow infectious viruses, infections with powerful inflammatory effects in blood vessels
    • electromagnetic fields
    • head injury

Factors which at the time of diagnosis indicate a higher risk for a more rapid decline:

  • Older age
  • Male gender
  • Presence of hypertension
  • Signs of motor control/coordination loss
  • Tremor
  • Social withdrawal
  • Anorexia with severe weight loss
  • Sensory problems: hearing loss, decline in reading ability
  • General physical debility

More Information:
http://www.ethnicelderscare.net/ethnicity&dementia.htm

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Last Modified: July 2004


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